Abstract:
Acute coronary syndrome is one of the world’s major killers and has a high morbidity and mortality
rates. The aim of this study to assess the role of different markers used in the diagnosis of acute
coronary syndrome. Descriptive case - control study conducted during the period from October 2015
to August 2016 to determine the plasma levels of total creatine kinase (CK), creatine kinase – MB
(CK-MB) and troponin I as diagnostic markers for acute coronary syndrome. Statistical package for
social science (SPSS version 17) computer software was used for data analysis. The result of this study
showed significant high level of CK and CK-MB of the test group when compared with control group
and significant elevated means of plasma levels of total CK and CK-MB of myocardial infarction
patients when compared with unstable angina within test group. The result of this study also revealed
that; the plasma troponin I is positive in myocardial infarction when compared with unstable angina
in test group. Conclusion: Qualitative assessment of plasma level of cardiac troponin and measuring
of the plasma activity of total CK and CK-MB are helpful markers for diagnosis of patients with acute
coronary syndrome.
